hrp0086fc8.4 | Growth: Clinical | ESPE2016

Genetic Insights from Children with Idiopathic Short Stature in the EPIGROW Study

Perchard Reena , Murray Philip , Payton Anthony , Clayton Peter

Background: EPIGROW was a prospective European epidemio-genetic study in children with idiopathic short stature (ISS).Objectives: To identify (1) differences in frequencies of single nucleotide polymorphisms (SNPs) in growth related genes between ISS children and controls, and (2) associations between growth characteristics, IGF status and SNPs in these genes.Methods: Sequence data from EPIGROW was used to determine the difference ...